Students will 1) describe parameters involved in simulating an action potential; 2) generate a hypothesis about the behavior of the system; 3) analyze the effect of stimulus intensity, reversal potential, and conductance.

Thus activity is designed for a small interdisciplinary class of first year graduate students and needs at least 2 hours for completion. Students need experience with MATLAB, numerical integration, plotting, programming, and neuroscience. This activity is provided early in the semester as an introduction to seminal models in neuroscience and biomechanics.

The activity begins with a brief discussion on the hodgkin-huxley model based on a provided reading.

Students begin lab worksheet, and check in with facilitator at different checkpoints through the activity. Questions are answered as a group.

Common areas of confusion are identification of parameters, and coding needed for parameter analysis.

If students complete all questions in the activity, they have met the goals of the activity.

http://www.math.mcgill.ca/gantumur/docs/reps/RyanSicilianoHH.pdf