Example Genomic Activities
Getting Started
A major goal of our Big Science at Small Schools initiative is to advance genomics pedagogy through the development of inquiry-based integrated instructional units (I3Us).
Results 1 - 10 of 14 matches
Using Metagenomics to Investigate Microbial Diversity part of Genomics Instructional Units Minicollection
David Esteban, Vassar College; Lois Banta, Williams College; Doyle Ward, Broad Institute; Bruce Birren, Broad Institute; Elizabeth Collins, Vassar College
Using Winogradsky columns, a soil enrichment culture, students explore microbial diversity through metagenomics. The Winogradsky column is a complex community of interacting microorganisms. In a community such as ...
Constructing and using a PAM style scoring matrix part of Genomics Instructional Units Minicollection
Eliot Bush, Harvey Mudd College
Comparison of a Highly Polymorphic Olfactory Receptor Gene Subfamily in Genetically Diverse Dog Breeds part of Genomics Instructional Units Minicollection
Lois Banta, Williams College; Norm Bell, Williams College; Duane Bailey, Williams College
Students design primers specific for a particular subfamily of polymorphic canine olfactory genes, use PCR to amplify the genes, and compare the sequences of the products obtained for a diverse population of dogs.
Comparison of Protein Sequences: BLAST searching and Phylogenetic Tree Construction part of Genomics Instructional Units Minicollection
Wade Powell, Kenyon College
This laboratory exercise is a guided discovery of computational methods for comparing protein sequences. Students perform BLAST searches of reported CYP1A sequences and construct phylogenetic trees using CYP1A amino acid sequences from various vertebrate species, especially those with multiple CYP1A paralogs.
Behavior, Neuroanatomy, Genomics: what can we learn from mouse mutants? part of Genomics Instructional Units Minicollection
Carol Ann Paul, Wellesley College; Ginny Quinan, Wellesley College
In this sequence of labs students will be provided a mutant mouse with an unspecified motor mutation and its wild-type control. The goal of this sequence is to identify and characterize the mutant using behavior, neuroanatomy and genomics.
Modeling Molecular Evolution part of Genomics Instructional Units Minicollection
Jodi Schwarz, Vassar College; Marc L. Smith, Vassar College
Biology and Computer Science majors collaborate to model the process of mutation at the DNA level, and examine the consequences at the protein level.
Phylogenetic analysis of the bony fishes: Morphological and mtDNA sequence comparisons part of Genomics Instructional Units Minicollection
Erica Crespi, Washington State University
This three-four week inquiry-based module is designed to teach students basic concepts, quandaries, and methodology of phylogenetics in a format that integrates wet-lab, bioinformatics, and lecture/discussion.
Human Single Nucleotide Polymorphism Determination part of Genomics Instructional Units Minicollection
Sarah Deel, Carleton College; Susan Singer, Carleton College; Debby Walser-Kuntz, Carleton College
In this laboratory exercise, students determine which allelic form of a particular single nucleotide polymorphism (SNP) they have (one located in an intron, and not associated with any known phenotype). Students ...
Reconstructing the Evolution of Cauliflower and Broccoli part of Genomics Instructional Units Minicollection
Susan Singer, Carleton College; Sarah Deel, Carleton College; Debby Walser-Kuntz, Carleton College
This laboratory exercise focuses on the connections between plant genetics and morphology.
Exploring the Chamaecrista Gene Space part of Genomics Instructional Units Minicollection
Susan Singer, Carleton College; Benjamin J. Taylor, University of Wisconsin, Madison; Cathy Manduca, SERC; Sean Fox, SERC; Ellen Iverson, SERC
Whole transcriptome sequencing can provide undergraduates with large data sets forming a foundation for authentic research experiences in the context of a teaching lab. This laboratory experience integrates in ...