CURE Examples



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Design2Data
Ashley Vater, University of California-Davis
The D2D program is centered around an undergraduate-friendly protocol workflow that follows the design-build-test-learn engineering framework. This protocol has served as the scaffold for a successful undergraduate training program and has been further developed into courses that range from a 10-week freshman seminar to a year-long, upper-division molecular biology course. The overarching research goal of this CURE probes the current predictive limitations of protein-modeling software by functionally characterizing single amino acid mutants in a robust model system. The most interesting outcomes of this project are dependent on large datasets, and, as such, the project is optimal for multi-institutional collaborations.

Discipline: Chemistry:Biochemistry, Chemistry, Life Sciences:Molecular Biology
Core Competencies: Using mathematics and computational thinking, Constructing explanations (for science) and designing solutions (for engineering), Analyzing and interpreting data, Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering), Developing and using models
Nature of Research: Wet Lab/Bench Research, Basic Research, Applied Research
Target Audience: Upper Division, Non-major, Major, Introductory
CURE Duration: A full term, Multiple terms

Laser spectroscopy of atmospherically relevant molecules and clusters in helium nanodroplets
Paul Raston, James Madison University
Superfluid helium nanodroplets present an ideal medium for the study of chemical dynamics at the molecular level. Their low temperature, enormous heat conductivity, and weakly interacting nature allow for the investigation of various things, such as how molecular rotation is effected by a solvent, and how molecules interact with each other. These two topics will be addressed in the lab by (1) measuring the spectra of unexplored molecules in helium nanodroplets and determining their rotational constants; this data will then be used to test known models describing the interaction between the molecule and helium solvent, and (2) synthesizing and characterizing unexplored molecular clusters in an effort to better understand molecular solvation; students will solvate the "unexplored molecule" with an atmospherically relevant species (O2, N2, H2O), and investigate the resulting clusters with laser Stark spectroscopy.

Discipline: Chemistry:Physical Chemistry
Core Competencies: Using mathematics and computational thinking, Constructing explanations (for science) and designing solutions (for engineering), Analyzing and interpreting data, Developing and using models, Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Basic Research
State: Virginia
Target Audience: Upper Division, Non-major, Major
CURE Duration: A few class periods, Multiple terms

Investigating local climate change impacts in a STEM first year learning community
Mara Brady, California State University-Fresno
still in progress...

Discipline: Environmental Science:Water Quality and Quantity, Global Change and Climate, Chemistry:Environmental Chemistry, Environmental Science:Waste, Soils and Agriculture, Geoscience:Soils, Geoscience, Life Sciences:Ecology, Geoscience:Biogeosciences, Environmental Science, Land Use and Planning, Sustainability, Air Quality
Core Competencies: Using mathematics and computational thinking, Analyzing and interpreting data, Asking questions (for science) and defining problems (for engineering), Constructing explanations (for science) and designing solutions (for engineering), Planning and carrying out investigations
Nature of Research: Applied Research, Field Research
Target Audience: Major
CURE Duration: Multiple terms

Photocatalytic degradation of model compounds
Sarah St. Angelo, Dickinson College
This CURE is intended for a junior/senior level inorganic chemistry laboratory. Students will synthesize various composite nanomaterials than can be tested for photocatalytic activity for the degradation of model compounds (organic dye molecules). The components of the nanocomposites will be varied and the effects on the photocatalysis will be measured. Students will synthesize the nanocomposites and characterize them with several techniques useful to materials chemists, such as SEM, XRD, and AA.

Discipline: Chemistry:Analytical Chemistry, Inorganic Chemistry, Physical Chemistry, Chemistry
Core Competencies: Analyzing and interpreting data, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Applied Research
State: Pennsylvania
Target Audience: Major, Upper Division
CURE Duration: Half a term, Multiple terms

TRANSFER STUDENT CURE: Multi-organismal genomic analysis of molecular determinants of protein assembly.
Dylan Murray, University of California-Davis

Discipline: Chemistry, Biochemistry, Life Sciences:Cell Biology, Molecular Biology, Life Sciences, Plant Biology, Genetics, Chemistry:Physical Chemistry
Core Competencies: Analyzing and interpreting data, Planning and carrying out investigations
Nature of Research: Basic Research
State: California
Target Audience: Introductory
CURE Duration: Multiple terms

Animal Genome to Phenome - A CURE for food security
Mulumebet Worku, North Carolina A & T State University

Discipline: Chemistry:Biochemistry, Life Sciences:Cell Biology, Genetics, Life Sciences, Molecular Biology
Core Competencies: Developing and using models, Analyzing and interpreting data, Asking questions (for science) and defining problems (for engineering), Using mathematics and computational thinking
Nature of Research: Informatics/Computational Research, Basic Research, Applied Research
State: North Carolina
Target Audience: Major, Introductory
CURE Duration: Multiple terms