CURE Examples
Discipline Show all
Core Competencies
- Asking questions (for science) and defining problems (for engineering) 11 matches
- Developing and using models 4 matches
- Planning and carrying out investigations 9 matches
- Analyzing and interpreting data 11 matches
- Using mathematics and computational thinking 5 matches
- Constructing explanations (for science) and designing solutions (for engineering) 5 matches
Nature of Research Show all
Applied Research
13 matchesState
DisciplineResults 1 - 10 of 13 matches
Design2Data
Ashley Vater, University of California-Davis
The D2D program is centered around an undergraduate-friendly protocol workflow that follows the design-build-test-learn engineering framework. This protocol has served as the scaffold for a successful undergraduate training program and has been further developed into courses that range from a 10-week freshman seminar to a year-long, upper-division molecular biology course. The overarching research goal of this CURE probes the current predictive limitations of protein-modeling software by functionally characterizing single amino acid mutants in a robust model system. The most interesting outcomes of this project are dependent on large datasets, and, as such, the project is optimal for multi-institutional collaborations.
Core Competencies: Using mathematics and computational thinking, Constructing explanations (for science) and designing solutions (for engineering), Analyzing and interpreting data, Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering), Developing and using models
Nature of Research: Wet Lab/Bench Research, Basic Research, Applied Research
Target Audience: Upper Division, Non-major, Major, Introductory
CURE Duration: A full term, Multiple terms
Water in Gen Chem
Ruthanne Paradise, University of Massachusetts-Amherst
Core Competencies: Asking questions (for science) and defining problems (for engineering), Planning and carrying out investigations, Analyzing and interpreting data
Nature of Research: Applied Research
State: Massachusetts
Target Audience: Introductory, Non-major, Major
CURE Duration: A full term
Synthesis and characterization of KLVFF derivatives: Propensity to aggregate?
Kalyani Maitra, California State University-Fresno
The aggregation of β-amyloid peptide plaques in the brain plays an important role in Alzheimer's disease (AD). Studies have shown that the specific peptide sequence of KLVFF (lysine, leucine, valine, phenylalanine, phenylalanine) has an important role in β-amyloid formation. In this research, pentapeptide derivatives of KLVFF containing nonpolar, hydrophobic amino acids will be synthesized and characterized by 1H-NMR spectroscopy. NMR-based structural studies will be done to understand the structure-function/activity relationship of these polypeptide chains in various solvents. This will provide a deeper insight about the process of aggregation of proteins in various physiological environment and its critical role in AD.
Nature of Research: Applied Research, Basic Research, Wet Lab/Bench Research
Target Audience: Upper Division, Major
Fruit Flies as a Model of Human Neurodegenerative Disease
Joy Goto, California State University-Fresno
Upper-division biochemistry and chemistry majors will learn and iteratively apply the techniques of protein purification, DNA and protein gels, Western blot, DNA isolation, transformation, enzyme characterization to research the utility of fruit fly (D. melanogaster) to model the human neurodegenerative disease (e.g. ALS - Lou Gehrig's, Parkinson's Disease, Alzheimer's Disease).
Nature of Research: Wet Lab/Bench Research, Applied Research
State: California
Target Audience: Major
Investigating local climate change impacts in a STEM first year learning community
Mara Brady, California State University-Fresno
still in progress...
Core Competencies: Using mathematics and computational thinking, Analyzing and interpreting data, Asking questions (for science) and defining problems (for engineering), Constructing explanations (for science) and designing solutions (for engineering), Planning and carrying out investigations
Nature of Research: Applied Research, Field Research
Target Audience: Major
CURE Duration: Multiple terms
Polymer/Materials Structure-Property Relationship Investigations for General Chemistry Students
Zuleikha Kurji, Saint Marys College of California
Core Competencies: Analyzing and interpreting data, Constructing explanations (for science) and designing solutions (for engineering), Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Wet Lab/Bench Research, Applied Research
State: California
Target Audience: Introductory, Non-major, Major
CURE Duration: A few class periods, Half a term
Chemical Analysis of Coffee Beans in Collaboration with a Local Roaster
Susan Oxley, St. Marys University
This CURE will take place in an Analytical Chemistry course. Students in the CURE course will collaborate with a local coffee roaster to develop a research question related to quantifying components of coffee beans. Using standard methods of analysis, students will work in groups to perform the analysis and validate their results. The outcome of the research will be a report to the coffee roaster.
Core Competencies: Using mathematics and computational thinking, Analyzing and interpreting data, Constructing explanations (for science) and designing solutions (for engineering), Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Applied Research, Wet Lab/Bench Research
State: Texas
Target Audience: Major, Upper Division
CURE Duration: A full term
Integration of a nanoparticles-based biosensing assay into a capillary column
Swarnapali Indrasekara, University of North Carolina at Charlotte
In this CURE project, junior and senior level chemistry students will be introduced to nanochemistry and its application in interdisciplinary research. Students will learn the use of chemistry concepts they have already learnt and also new spectroscopy and physical chemistry concepts. They will use that knowledge to develop an optical biosensor using nanoparticles in a capillary column as a potential point-of-care assay format.
Core Competencies: Analyzing and interpreting data, Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Applied Research, Wet Lab/Bench Research
State: North Carolina
Target Audience: Major, Upper Division
Effect of Short Blood Sample on Patient Results Validity
Anna Marti-Subirana, Phoenix College
This CURE addresses how body fluid short sampling affects result interpretation and diagnostics. Short sampling can lead to false result interpretation and misdiagnosis. No data are available on the impact of short sampling and clinical diagnostics.
Core Competencies: Analyzing and interpreting data, Planning and carrying out investigations, Using mathematics and computational thinking, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Applied Research
State: Arizona
Target Audience: Major
CURE Duration: A full term
Photocatalytic degradation of model compounds
Sarah St. Angelo, Dickinson College
This CURE is intended for a junior/senior level inorganic chemistry laboratory. Students will synthesize various composite nanomaterials than can be tested for photocatalytic activity for the degradation of model compounds (organic dye molecules). The components of the nanocomposites will be varied and the effects on the photocatalysis will be measured. Students will synthesize the nanocomposites and characterize them with several techniques useful to materials chemists, such as SEM, XRD, and AA.
Core Competencies: Analyzing and interpreting data, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Applied Research
State: Pennsylvania
Target Audience: Major, Upper Division
CURE Duration: Half a term, Multiple terms