CURE Examples
Core Competencies
- Asking questions (for science) and defining problems (for engineering) 2 matches
- Planning and carrying out investigations 3 matches
- Analyzing and interpreting data 2 matches
- Using mathematics and computational thinking 1 match
- Constructing explanations (for science) and designing solutions (for engineering) 1 match
Target Audience
CURE Duration
Nature of ResearchResults 1 - 3 of 3 matches
Effects of Antimalarial Drugs (Artemisinin class) on Prostate Cancer Cells.
Dolapo Adedeji, Elizabeth City State University
Prostate cancer is the second leading cause of cancer-related deaths in American men and the most non-skin cancer. It is a low-growing tumor occurring in older men and the most common type of non-skin cancer. Students will gain understanding in mammalian cell culturing, cell growth maintenance, cell seeding and be able to determine the concentration at which each drug concentration inhibit cell proliferation.
Core Competencies: Planning and carrying out investigations
Nature of Research: Wet Lab/Bench Research, Applied Research
State: North Carolina
Target Audience: Upper Division, Major
CURE Duration: A full term
Integration of a nanoparticles-based biosensing assay into a capillary column
Swarnapali Indrasekara, University of North Carolina at Charlotte
In this CURE project, junior and senior level chemistry students will be introduced to nanochemistry and its application in interdisciplinary research. Students will learn the use of chemistry concepts they have already learnt and also new spectroscopy and physical chemistry concepts. They will use that knowledge to develop an optical biosensor using nanoparticles in a capillary column as a potential point-of-care assay format.
Core Competencies: Analyzing and interpreting data, Planning and carrying out investigations, Asking questions (for science) and defining problems (for engineering)
Nature of Research: Applied Research, Wet Lab/Bench Research
State: North Carolina
Target Audience: Major, Upper Division
Understanding Noncovalent Interactions and Binding through PRRSM
Amanda Hargrove, Duke University
This CURE was designed to increase instruction on noncovalent interactions and intermolecular forces, provide laboratory experiences in biochemistry and chemical biology, and deliver a more consistent chemistry research experience to undergraduates at Duke University while staying within the existing curriculum. First, the concept of noncovalent interactions is visualized in an applied setting by examining 3D structures of small molecule:RNA interactions through a portable virtual reality (VR) environment. Next, using knowledge gained in the Hargrove lab regarding small molecule:RNA interactions along with the literature examples, teams of students evaluate known small molecule:RNA interactions, pose original scientific questions, and design a hypothesis-driven experiment that can be readily tested with commercially available materials using a standard fluorimeter or plate reader. These experiments directly contribute to research that examines patterns in the recognition of RNA structure by small molecules, and the students are able to assess their contribution to this ongoing interdisciplinary project.
Core Competencies: Analyzing and interpreting data, Using mathematics and computational thinking, Planning and carrying out investigations, Constructing explanations (for science) and designing solutions (for engineering), Asking questions (for science) and defining problems (for engineering)
Nature of Research: Basic Research, Wet Lab/Bench Research
State: North Carolina
Target Audience: Major, Upper Division
CURE Duration: Half a term