Using Metagenomics to Investigate Microbial Diversity part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
Using Winogradsky columns, a soil enrichment culture, students explore microbial diversity through metagenomics. The Winogradsky column is a complex community of interacting microorganisms. In a community such as ...

Expression of gerontogenes in neurons: A comparative genomic approach to studying the role of the nervous system in lifespan/aging part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
This multi-week laboratory module is appropriate for an intermediate-level neuroscience and behavior course. Students design behavioral experiments in wildtype and mutant C. elegans with defects in neurally-expressed genes implicated in aging. Students then use bioinformatic and comparative genomic tools to explore orthologous genes in at least ten different animal taxa.

Phylogenetic analysis of the bony fishes: Morphological and mtDNA sequence comparisons part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
This three-four week inquiry-based module is designed to teach students basic concepts, quandaries, and methodology of phylogenetics in a format that integrates wet-lab, bioinformatics, and lecture/discussion.

Comparison of Protein Sequences: BLAST searching and Phylogenetic Tree Construction part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
This laboratory exercise is a guided discovery of computational methods for comparing protein sequences. Students perform BLAST searches of reported CYP1A sequences and construct phylogenetic trees using CYP1A amino acid sequences from various vertebrate species, especially those with multiple CYP1A paralogs.

Brassica oleracea Subspecies part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
Return to Main Lab Page Brassica species- A grocery store still life, primarily Brassica oleracae Brassica oleracea ssp. botrytis - Cauliflower Brassica oleracea ssp. italica - Broccoli Brassica oleracea ssp. ...

Constructing and using a PAM style scoring matrix part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection

Comparison of a Highly Polymorphic Olfactory Receptor Gene Subfamily in Genetically Diverse Dog Breeds part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
Students design primers specific for a particular subfamily of polymorphic canine olfactory genes, use PCR to amplify the genes, and compare the sequences of the products obtained for a diverse population of dogs.

Human Single Nucleotide Polymorphism Determination part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
In this laboratory exercise, students determine which allelic form of a particular single nucleotide polymorphism (SNP) they have (one located in an intron, and not associated with any known phenotype). Students ...

Reconstructing the Evolution of Cauliflower and Broccoli part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
This laboratory exercise focuses on the connections between plant genetics and morphology.

Images of Arabidopsis Wild-type and Mutant Plants part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
Return to Main Lab Page Photo of a wild-type Arabidopsis inflorescence. Photo of a apetala1 mutant Arabidopsis inflorescence. Photo of a apetala1 cauliflower mutant Arabidopsis inflorescence. SEM of a wild-type ...