CURE Examples


Results 1 - 10 of 24 matches

A Bioinformatic Look at Iron Uptake in Insects
Emily Ragan, Metropolitan State University of Denver
Students will perform BLAST searches, make phylogenetic trees, identify putative orthologs, and investigate secondary structure elements of 5' untranslated regions (UTRs). The sequences used will be related to iron uptake in insects.

Discipline: Chemistry:Biochemistry, Life Sciences:Molecular Biology
Core Competencies: Analyzing and interpreting data
Nature of Research: Informatics/Computational Research
State: Colorado
Target Audience: Major, Upper Division
CURE Duration: Half a term

Exploring the Structure-Function Relationship in RNA Biochemistry

Discipline: Chemistry:Biochemistry, Life Sciences:Molecular Biology
Core Competencies: Asking questions (for science) and defining problems (for engineering), Developing and using models, Planning and carrying out investigations, Analyzing and interpreting data, Using mathematics and computational thinking, Constructing explanations (for science) and designing solutions (for engineering)
Nature of Research: Basic Research
State: Colorado
Target Audience: Major, Upper Division
CURE Duration: Half a term

Climate change related shifts in ecosystem services
andrew harwood, Clark College
This CURE allows students to explore how climate change affects local and migratory wildlife habitat useage patterns, and the associated ecosystem services migrating wildlife such as salmon provide to Pacific Northwest communities.

Discipline: Life Sciences:Ecology, Evolution, Life Sciences, Statistics
Core Competencies: Asking questions (for science) and defining problems (for engineering), Developing and using models, Planning and carrying out investigations, Analyzing and interpreting data, Using mathematics and computational thinking, Constructing explanations (for science) and designing solutions (for engineering)
Nature of Research: Applied Research, Basic Research, Field Research, Informatics/Computational Research
State: Washington
Target Audience: Major, Non-major
CURE Duration: A few class periods, Half a term, A full term, Multiple terms

Applied Metagenomics
Stokes Baker, University of Detroit Mercy
The long-term objective of the proposal is to develop a metagenomics course that will support the goals of the ReBUILDetroit program at the University of Detroit Mercy. Genomics technologies are now revolutionizing biomedical research due to advancements in next genera¬tion sequencing (NGS) technologies. As a result, undergraduates that have significant exposure to metagenomics will be better prepared to enter graduate school. To meet the objective, high-impact activities that have been shown to increase retention among underrepresented minorities (URM) and women will be built into the pedagogical approaches. A new course-based undergraduate research experience (CURE) course, entitled "Applied Metagenomics", will be created where undergraduates will be conducting authentic research that directly impacts their local community. Students will work on common projects and write laboratory reports in a cooperative manner within their learning communities. This course will advance public health because a diverse pool of future biomedical researchers will gain expertise in an emerging technology. The course involves using 16S rRNA metagenomics to evaluate the potential public health impacts of ponds found in city parks. The students will collect samples, isolate bacterial DNA, and make 16S rRNA gene libraries. A new NGS technology (the MinION by Oxford Nanopore, Oxford UK) will be used to sequence the students' libraries. The students will use the supercomputing resources provided by Argonne National Laboratory to publicly archive their data (thus directly contributing to the scientific community) and to analyze their data. The effectiveness of the instructional materials and pedagogies will be evaluated using standardized instruments and contemplation writing assignments. The results and instructional materials will be disseminated in peer-reviewed venues.

Discipline: Environmental Science:Water Quality and Quantity, Land Use and Planning, Life Sciences:Ecology, Microbiology, Life Sciences
Core Competencies: Asking questions (for science) and defining problems (for engineering), Planning and carrying out investigations, Analyzing and interpreting data, Using mathematics and computational thinking
Nature of Research: Applied Research, Field Research
State: Michigan
Target Audience: Major, Upper Division
CURE Duration: A full term

Nontraditional use of Silver Diamine Fluoride Applications in Patients of Need.
Amy Ewing Johnson, Clark College
A longitudinal study by which students implement and analyze the application of silver diamine fluoride on more nontraditional (permanent versus deciduous) tooth surfaces diagnosed with dental decay, where patients have no better viable option after fully informed patient consultation with a dental hygienist and diagnosis from a dentist. Essential to the study is the follow up evaluation on the efficacy of treated surfaces over a long period of time (3-5 years) to better determine the reliability and stability of silver diamine fluoride application as a stop gap restorative option for patients who can not access or afford traditional restorative methods in dentistry.

Urban Wildlife Information Network (UWIN) CURE
Sarah St. Onge, University of Colorado Denver/Anschutz Medical Campus

Molecular and Phenotypic Chararcterization of Phenylalanine hydroxylase in C. elegans
Mark Haefele, Community College of Denver

Discipline: Life Sciences:Cell Biology, Genetics, Molecular Biology
Core Competencies: Asking questions (for science) and defining problems (for engineering), Analyzing and interpreting data, Constructing explanations (for science) and designing solutions (for engineering)
Nature of Research: Basic Research
State: Colorado
Target Audience: Major, Non-major
CURE Duration: A full term