Earth and Space Science (ESS) Scaffolded Inquiry Labs are a collection of labs designed for students to apply different aspects of the process of science with progressively reduced instructional scaffolding while also focusing on scientific and quantitative literacies. The collection currently includes nine modular labs with topics appropriate for geology, oceanography, astronomy, and earth science courses. The modularity allows for shortening as well as enhancement of student-centered lectures. Adhering to best practices for accessibility, the labs leverage online data sets and do not require complex analysis tools or other materials. To help students better differentiate aspects of the process of science, each lab has 3-5 questions that require students to reflect on their current stage in process of science (e.g., asking a scientific question, determining the methods, making observations and collecting data, analyzing data and developing conclusions, sharing results and conclusions). In addition, each lab includes 3-7 questions focused on 2-3 scientific and quantitative literacies including: assumptions, averages, percentages, causal relationships, causation versus correlation, unit conversion, graph reading, and observations versus interpretations. Pilot data from non-STEM majors in introductory earth and space science (ESS) courses at a two-year college (TYC) suggest the labs are successful in achieving the learning goals. In the pilot study with 125 lab attempts across six labs, students demonstrated high proficiency, correctly answering 92% of the process of science questions and 85% of the scientific and quantitative literacy questions, ranging from 74% to 95% for different literacies. The success of these labs suggests they are a versatile solution for instructors seeking to integrate scientific and quantitative literacy into introductory science courses.