Squid-Vibrio Symbiosis

Online Collection

General Information - For Educators - Advanced Resources - Scientists

Learn More About Squid-Vibrio Symbiosis...


An adult Euprymna scolopes, a species of bioluminescent sepiolid squid
This image shows an adult Euprymna scolopes (Hawaiian bobtail squid), a species of bioluminescent sepiolid squid. Image Credit: M. J. McFall-Ngai and E. G. Ruby, University of Hawaii. Provided courtesy of the National Science Foundation.
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Explore Squid-Vibrio Symbiosis & Bioluminescence in the Classroom


Colonies of the bioluminescent marine bacterium Vibrio fischeri
Colonies of the bioluminescent marine bacterium Vibrio fischeri. The photograph of colonies growing on agar (left) was taken with a light source. The photograph of colonies on the right was taken using their own bioluminescence as a light source. Image Credit: J. W. Hastings, Harvard University, through E. G. Ruby, University of Hawaii. Provided courtesy of the National Science Foundation.
  • Cephalopod Lesson Plans. This collection of lesson plans, created by the Bermuda Biological Station for Research, highlights color change in cephalopods. This page provides links to each lesson... (more info)
  • Glow: Living Lights. This 48-page Teacher's Guide accompanies the "Glow: Living Lights" exhibit at the San Diego Natural History Museum. In PDF format, the guide contains 12 lesson plans that... (more info)
  • Isolation of Pure Cultures Of Bacteria: Vibrio phosphoreum from Squid or Ocean Fish. This educational web page presents an isolation protocol for the bioluminescent bacteria Vibrio phosphoreum. It includes an introduction to Vibrio, safety concerns... (more info)
  • Light at the Bottom of the Deep, Dark Ocean?. This Ocean Explorer interactive, hands-on lesson plan (PDF) leads students on an exploration of deepwater adaptations by addressing the focus question: What... (more info)
  • Squid Lab. This online handbook features a downloadable PDF of pre-and post-visit activities for the Squid Lab, a traveling outreach program hosted by the National Aquarium in... (more info)
  • Who Has the Light?. This NOAA classroom activity explores bioluminescence. This PDF addresses: Which deep-sea organisms are capable of bioluminescence, and how does this ability benefit... (more info)
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Advanced Resources


Ventral dissection of an adult Euprymna scolopes
Ventral dissection of an adult Euprymna scolopes, a species of bioluminescent sepiolid squid. The mantle cavity is visible, including the interior bilobed light organ that allows the squid to produce bioluminescent light. Image Credit: M. J. McFall-Ngai and E. G. Ruby, University of Hawaii. Provided courtesy of the National Science Foundation.
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Meet the Scientists


  • Dr. Cheryl A. Whistler. This University of New Hampshire faculty page features a summary of Dr. CA Whistler's current research. Using the symbiosis of the bioluminescent bacterium, Vibrio... (more info)
  • Eric V. Stabb, Ph.D. . This University of Georgia faculty page features Eric V. Stabb, Assistant Professor of Microbiology. His research focuses on the light organ symbiosis between the... (more info)
  • Margaret McFall-Ngai Lab. (more info)
  • The Ruby Lab. This University of Wisconsin-Madison Medical Microbiology and Immunology website features the Edward G. Ruby Lab. The Ruby Lab is attempting to define the behavioral, physiological... (more info)
  • Visick Lab: Home of the Vibrio-Euprymna Symbiosis. This website features general information about the lab of Karen Visick, which studies the genes needed to establish an interaction between the small Hawaiian squid Euprymna... (more info)
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Additional Resources


For additional resources about Squid-Vibrio symbiosis, search the Microbial Life collection.