Vibrio fischeri lipopolysaccharide induces developmental apoptosis, but not complete morphogenesis, of the Euprymna scolopes symbiotic light organ.

JS Foster, MA Apicella, MJ McFall-Ngai, Developmental Biology

This Developmental Biology scholarly article investigates the role of lipopolysaccharide (LPS) during initiation of the association between the squid host Euprymna scolopes and its bacterial partner Vibrio fischeri. During this process, the bacteria induce dramatic morphogenesis of the host symbiotic organ, a portion of which involves the signaling of widespread apoptosis of the cells in a superficial ciliated epithelium on the colonized organ. Data shows that LPS was able to induce apoptosis, but did not induce the full morphogenesis of the ciliated surface, suggesting that multiple signals are necessary to mediate the development of this animalľbacterial mutualism. A subscription may be required to link to the full-text version of this article.

Subject: Biology:Ecology:Symbiotic Relations:Mutualism, Biology:Ecology:Metabolism, Habitats:Marine, Biology:Microbiology, Molecular Biology
Resource Type: Scientific Resources:Research Results
Grade Level: Graduate/Professional, College Upper (15-16), College Lower (13-14)
Topics: Biosphere:Ecology:Metabolism, Habitats:Marine, Biosphere:Molecular Biology, Ecology:Symbiotic Relations:Mutualism, Biosphere:Microbiology
Theme: Teach the Earth:Course Topics:Ecology