This is a review of DNA sequencing technologies published in The Journal of Experimental Biology in 2007. Several technologies are covered in detail - Sanger, 454, and polony approaches to sequencing by amplification; and single-molecule sequencing. This is followed by discussion of the need for (and applicability of new technologies in) additional microbial genome sequences, mutation screening, and metagenomics studies. This is an excellent resource for teachers and students planning research projects or preparing for a research career.
