Futterer O, Angelov A, Liesegang H, Gottschalk G, Schleper C, Schepers B, Dock C, Antranikian G, Liebl W. , Proceedings of the National Academy of Sciences of the United States
This scientific paper describes the Picrophilaceae, which are the most acidophilic organisms known and amazingly, are able to grow at negative pH values. The authors deduce several features that may contribute to the thermoacidophilic survival strategy of P. torridus by sequencing and analyzing its 1.55-megabase genome. Specific adaptation mechanisms described and discussed include the structure and function of biomolecules, subcellular structures, physiology and metabolic features, and regulation of gene expression. A diagram illustrating the overview of the transport, central metabolism, and energy production in P. torridus is also included.
