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Expression of gerontogenes in neurons: A comparative genomic approach to studying the role of the nervous system in lifespan/aging part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
This multi-week laboratory module is appropriate for an intermediate-level neuroscience and behavior course. Students design behavioral experiments in wildtype and mutant C. elegans with defects in neurally-expressed genes implicated in aging. Students then use bioinformatic and comparative genomic tools to explore orthologous genes in at least ten different animal taxa.