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This journal article is a review of halophiles, which are salt-loving organisms that inhabit hypersaline environments. The resource introduces hypersaline habitats and osmotic protection of inhabiting cells and offers examples of various halophiles. Eukaryotic halophiles discussed are algae, protozoa, fungi, and a few multicellular eukaryotes. Prokaryotic halophiles highlighted are cyanobacteria, sulfur-oxidizing bacteria, anaerobic bacteria, Archaea, phototrophic bacteria, aerobic and facultative anaerobic Gram-negative bacteria, Gram-positive bacteria, and Halobacteria.