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Human Single Nucleotide Polymorphism Determination part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
In this laboratory exercise, students determine which allelic form of a particular single nucleotide polymorphism (SNP) they have (one located in an intron, and not associated with any known phenotype). Students ...
Comparison of Protein Sequences: BLAST searching and Phylogenetic Tree Construction part of Teaching Genomics at Small Colleges:Genomics Instructional Units Minicollection
This laboratory exercise is a guided discovery of computational methods for comparing protein sequences. Students perform BLAST searches of reported CYP1A sequences and construct phylogenetic trees using CYP1A amino acid sequences from various vertebrate species, especially those with multiple CYP1A paralogs.